catalog number :
MBS8245848
products full name :
Anti-PIMT Antibody
products short name :
[PIMT]
products name syn :
[HCA137; NCOA6IP; PIMT; Trimethylguanosine synthase; CLL-associated antigen KW-2; Cap-specific guanine-N2 methyltransferase; Hepatocellular carcinoma-associated antigen 137; Nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif; PIMT; PIPMT]
other names :
[trimethylguanosine synthase isoform 2; Trimethylguanosine synthase; trimethylguanosine synthase; trimethylguanosine synthase 1; CLL-associated antigen KW-2; Cap-specific guanine-N2 methyltransferase; Hepatocellular carcinoma-associated antigen 137; Nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif; PIMT; PIPMT]
products gene name :
[TGS1]
other gene names :
[TGS1; TGS1; PIMT; PIPMT; NCOA6IP; HCA137; NCOA6IP; PIMT; PIMT; PIPMT]
uniprot entry name :
TGS1_HUMAN
specificity :
Recognizes endogenous levels of PIMT protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1/500 - 1/2000. IHC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant full length protein of human PIMT
products description :
Rabbit polyclonal antibody to PIMT
ncbi acc num :
NP_001304831.1
ncbi gb acc num :
NM_001317902.1
ncbi pathways :
Activation Of Gene Expression By SREBF (SREBP) Pathway (1270039); BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway (1269872); Circadian Clock Pathway (1269871); Developmental Biology Pathway (1270302); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (1270010); Gene Expression Pathway (1269649); Generic Transcription Pathway (1269650); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Metabolism Of Non-coding RNA Pathway (1269731)
uniprot summary :
PIMT: a nuclear protein and apparent methyltransferase. Binds S-adenosyl-L-methionine and RNA. Plays a role in transcriptional regulation. Interacts with NCOA, CBP, p300, and PPARBP. Ubiquitously expressed. High expression in heart, skeletal muscle, kidney, liver and placenta. Protein type: Nuclear receptor co-regulator; RNA processing; EC 2.1.1.-; Methyltransferase. Chromosomal Location of Human Ortholog: 8q11. Cellular Component: Cajal body; cytoplasm; cytosol; extracellular space; nucleolus; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex. Molecular Function: protein binding; RNA methyltransferase activity. Biological Process: cellular lipid metabolic process; regulation of transcription, DNA-dependent; ribonucleoprotein complex biogenesis and assembly; RNA capping; spliceosomal snRNP biogenesis; transcription, DNA-dependent