product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-H-Ras Antibody
catalog :
MBS8245805
quantity :
0.05 mL
price :
175 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of H-Ras expression in SKOV3 (A), mouse kidney (B), rat brain (C) whole cell lysates.
image 2 :
Immunohistochemical analysis of H-Ras staining in human gastric cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8245805
products type :
Antibody
products full name :
Anti-H-Ras Antibody
products short name :
[H-Ras]
products name syn :
[HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras]
other names :
[GTPase HRas isoform 1; GTPase HRas; GTPase HRas; Harvey rat sarcoma viral oncogene homolog; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras]
products gene name :
[HRAS]
other gene names :
[HRAS; HRAS; CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; HRAS1]
uniprot entry name :
RASH_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
170
specificity :
Recognizes endogenous levels of H-Ras protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1/500 - 1/2000; IHC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH-conjugated synthetic peptide of human H-Ras
products description :
Rabbit polyclonal antibody to H-Ras
ncbi gi num :
194363762
ncbi acc num :
NP_001123914.1
ncbi gb acc num :
NM_001130442.2
uniprot acc num :
P01112
ncbi pathways :
AGE-RAGE Signaling Pathway In Diabetic Complications (1319988); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); ARMS-mediated Activation Pathway (1269471); Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (1268798); Activation Of RAS In B Cells Pathway (1269187); Acute Myeloid Leukemia Pathway (83117); Acute Myeloid Leukemia Pathway (529); Adaptive Immune System Pathway (1269171); Alcoholism Pathway (585563); Alcoholism Pathway (587116)
ncbi summary :
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
size1 :
0.05 mL
price1 :
175 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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