product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-PRG2 Antibody
catalog :
MBS8245453
quantity :
0.05 mL
price :
175 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8245453 image 1
Western blot analysis of PRG2 expression in MCF7 (A), HL60 (B), mouse kidney (C), mouse heart (D) whole cell lysates.
image 2 :
MyBioSource MBS8245453 image 2
Immunohistochemical analysis of PRG2 staining in human gastric cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8245453
products type :
Antibody
products full name :
Anti-PRG2 Antibody
products short name :
[PRG2]
products name syn :
[MBP; Bone marrow proteoglycan; BMPG; Proteoglycan 2]
other names :
[bone marrow proteoglycan isoform 2 preproprotein; Bone marrow proteoglycan; bone marrow proteoglycan; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); Proteoglycan 2]
products gene name :
[PRG2]
other gene names :
[PRG2; PRG2; MBP; BMPG; MBP1; MBP; BMPG; EMBP; MBP]
uniprot entry name :
PRG2_HUMAN
clonality :
Polyclonal
host :
unknown
reactivity :
Human, Mouse
sequence length :
211
specificity :
Recognizes endogenous levels of PRG2 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1/500 - 1/2000; IHC: 1/50 - 1/200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit. Immunogen: Recombinant full length protein of human PRG2
products description :
Rabbit polyclonal antibody to PRG2
ncbi gi num :
342837699
ncbi acc num :
NP_001230174.1
ncbi gb acc num :
NM_001243245.2
uniprot acc num :
P13727
ncbi mol weight :
23,901 Da
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532)
ncbi summary :
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
uniprot summary :
Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
size1 :
0.05 mL
price1 :
175 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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