catalog number :
MBS8245274
products full name :
Anti-GSDML Antibody
products short name :
[GSDML]
products name syn :
[GSDML; Gasdermin-B; Gasdermin-like protein]
other names :
[gasdermin-B isoform 1; Gasdermin-B; gasdermin-B; gasdermin B; Gasdermin-like protein]
products gene name :
[GSDMB]
other gene names :
[GSDMB; GSDMB; GSDML; PP4052; PRO2521; GSDML]
uniprot entry name :
GSDMB_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of GSDML protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1/500 - 1/2000
image1 heading :
Western Blot (WB)
other info1 :
. Source: Rabbit. Immunogen: Recombinant full length protein of human GSDML
products description :
Rabbit polyclonal antibody to GSDML
ncbi acc num :
NP_001035936.1
ncbi gb acc num :
NM_001042471.1
ncbi summary :
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Sep 2009]
uniprot summary :
GSDML: May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. Belongs to the gasdermin family. 6 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 17q12. Cellular Component: cytoplasm. Biological Process: programmed cell death