catalog number :
MBS8244344
products type :
Blocking Peptide
products full name :
5-HT1F Blocking Peptide
products short name :
[5-HT1F]
products name syn :
[HTR1EL; 5-hydroxytryptamine receptor 1F; 5-HT-1F; 5-HT1F; Serotonin receptor 1F]
other names :
[5-hydroxytryptamine receptor 1F; 5-hydroxytryptamine receptor 1F; 5-hydroxytryptamine receptor 1F; 5-hydroxytryptamine receptor 1F; Serotonin receptor 1F]
products gene name :
[HTR1F]
other gene names :
[HTR1F; HTR1F; 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F; HTR1EL; 5-HT-1F; 5-HT1F]
uniprot entry name :
5HT1F_HUMAN
reactivity :
Human, Mouse, Rat, Monkey
form :
Lyophilized Powder
storage stability :
Shipping: Blue ice. Store at -20°C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.
other info2 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-5-HT1F Antibody reactivity.
ncbi pathways :
Amine Ligand-binding Receptors Pathway (1269553); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); GPCRs, Other Pathway (198765); Monoamine GPCRs Pathway (198861); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462)
uniprot summary :
5-HT(1F): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p12. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: serotonin binding; serotonin receptor activity. Biological Process: G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor signaling pathway; synaptic transmission