catalog number :
MBS824425
products type :
Blocking Peptide
products full name :
SCC-S2 Blocking Peptide
products short name :
[SCC-S2]
products name syn :
[Tumor necrosis factor alpha-induced protein 8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1]
other names :
[tumor necrosis factor alpha-induced protein 8 isoform b; Tumor necrosis factor alpha-induced protein 8; tumor necrosis factor alpha-induced protein 8; TNF-induced protein GG2-1; TNF alpha-induced protein 8; NF-kappa-B-inducible DED-containing protein; head and neck tumor and metastasis-related protein; tumor necrosis factor, alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1]
products gene name :
[TNFAIP8]
other gene names :
[TNFAIP8; TNFAIP8; NDED; GG2-1; SCCS2; SCC-S2; MDC-3.13; TNF alpha-induced protein 8; NDED]
uniprot entry name :
TFIP8_HUMAN
reactivity :
Human, Mouse, Rat, Bovine, Chicken, Pig
form :
Lyophilized powder
storage stability :
Shipped at 4°C. Store at -20°C for one year.
tested application :
Blocking (BL)
other info1 :
Source: Synthetic. Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
other info2 :
Directions for use: Blocking peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.
products description :
The peptide is used to block Anti-SCC-S2 Antibody reactivity.
ncbi acc num :
NP_001071122.1
ncbi gb acc num :
NM_001077654.2
uniprot summary :
TNFAIP8: Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 5q23.1. Cellular Component: cytoplasm. Molecular Function: caspase inhibitor activity. Biological Process: defense response to Gram-positive bacterium; interleukin-1 beta production; negative regulation of caspase activity; negative regulation of apoptosis