product summary
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company name :
MyBioSource
product type :
protein
product name :
SMRT Blocking Peptide
catalog :
MBS8243879
quantity :
1 mg
price :
160 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS8243879
products type :
Blocking Peptide
products full name :
SMRT Blocking Peptide
products short name :
[SMRT]
products name syn :
[CTG26; Nuclear receptor corepressor 2; N-CoR2; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor; SMRT; T3 receptor-associating factor; TRAC; Thyroid-, retinoic-acid-receptor-associated corepressor]
other names :
[Nuclear receptor corepressor 2; Nuclear receptor corepressor 2; nuclear receptor corepressor 2; nuclear receptor corepressor 2; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor; SMRT; T3 receptor-associating factor; TRAC; Thyroid-, retinoic-acid-receptor-associated corepressor]
products gene name :
[NCOR2]
other gene names :
[NCOR2; NCOR2; SMRT; TRAC; CTG26; SMRTE; TRAC1; N-CoR2; TNRC14; TRAC-1; SMAP270; SMRTE-tau; CTG26; N-CoR2; SMRT; TRAC]
uniprot entry name :
NCOR2_HUMAN
host :
Synthetic
reactivity :
Human
sequence length :
2525
purity :
>85%
form :
Lyophilized Powder
storage stability :
Ships on blue ice. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info2 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-SMRT Antibody reactivity.
ncbi gi num :
226713806
ncbi acc num :
Q9Y618.2
uniprot acc num :
Q9Y618
ncbi pathways :
Adipogenesis Pathway (198832); Androgen Receptor Signaling Pathway (198806); Chromatin Modifying Enzymes Pathway (1270434); Chromatin Organization Pathway (1270433); Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway (1268891); Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway (1268889); Delta-Notch Signaling Pathway (198879); Developmental Biology Pathway (1270302); Disease Pathway (1268854); Diseases Of Signal Transduction Pathway (1268855)
ncbi summary :
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
uniprot summary :
Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.
size1 :
1 mg
price1 :
160 USD
size2 :
5 mg
price2 :
305
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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