protein

14-3-3 theta/tau (pS232) Blocking Peptide

MBS8243321

1 mg

195 USD

Blocking Peptide

14-3-3 theta/tau (pS232) Blocking Peptide

[14-3-3 theta/tau]

[14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1]

[14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1]

[YWHAQ]

[YWHAQ; YWHAQ; 1C5; HS1; 14-3-3]

1433T_HUMAN

Synthetic

Human, Mouse, Rat, Bovine, Chicken, Pig

245

>85%

Lyophilized Powder

Shipped at 4°C. Store at -20°C for one year.

Blocking (BL)

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

The peptide is used to block Anti-14-3-3 theta/tau reactivity.

112690

P27348.1

P27348

Activation Of BAD And Translocation To Mitochondria Pathway (1270271); Activation Of BH3-only Proteins Pathway (1270270); Alpha6-Beta4 Integrin Signaling Pathway (198807); Apoptosis Pathway (1270262); Calcium Regulation In The Cardiac Cell Pathway (198906); Cell Cycle Pathway (1269741); Cell Cycle Checkpoints Pathway (1269742); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463)

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 2p25.1. Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex. Molecular Function: protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding. Biological Process: apoptosis; gene expression; negative regulation of transcription, DNA-dependent; programmed cell death; small GTPase mediated signal transduction; substantia nigra development; transcription initiation from RNA polymerase II promoter

1 mg

195 USD

5 mg

435