catalog number :
MBS8243231
products type :
Assay Kit
products full name :
Beta-Glucosidase Microplate Assay Kit
products short name :
[Beta-Glucosidase]
products name syn :
[EC 3.2.1.21; Beta-glucosidase; Amygdalase; Beta-D-glucoside glucohydrolase; Cellobiase; Gentobiase]
other names :
[beta-glucosidase, partial; beta-glucosidase]
other gene names :
[SCO6604; SC1F2.01]
storage stability :
Shipped and store at 4 degree C for 6 months.
tested application :
Functional Assay
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
products description :
Background/Introduction: beta-catenin is a 781 amino acid adherens junction protein that plays an important role in two unrelated cellular functions. Adherens junctions are critical for establishment and maintenance of epithelial layers, such as those found lining the surface of organs. Involved in both cell-cell adhesion and in the wnt/wg signaling pathway, beta-catenin can be found in the cytoplasm or the nucleus3. In the cytoplasm, beta-catenin is unstabilized by phosphorylation and association with E-cadherin. When beta-catenin translocates to the nucleus, it has comparatively low levels of phosphorylation. Wnt/wg signaling results in beta-catenin accumulation and transcriptional activation of specific target genes during development. Deregulation of beta-catenin signaling is an important event in the evolution a number of malignancies, including colon cancer4, melanoma, ovarian cancer5, and prostate cancer6. The homology between human, mouse and rat beta-catenin is 99.9%.
ncbi acc num :
NP_733708.1
ncbi gb acc num :
NC_003888.3
ncbi pathways :
Biosynthesis Of Secondary Metabolites Pathway (148761); Cyanoamino Acid Metabolism Pathway (8513); Cyanoamino Acid Metabolism Pathway (339); Metabolic Pathways (132075); Starch And Sucrose Metabolism Pathway (8517); Starch And Sucrose Metabolism Pathway (344)