product summary
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company name :
MyBioSource
product type :
other
product name :
Phenylalanine ammonia-lyase Microplate Assay Kit
catalog :
MBS8243227
quantity :
100 Assays
price :
360 USD
more info or order :
product information
catalog number :
MBS8243227
products type :
Assay Kit
products full name :
Phenylalanine ammonia-lyase Microplate Assay Kit
products short name :
[Phenylalanine ammonia-lyase]
products name syn :
[EC 4.3.1.24; Phenylalanine ammonia-lyase; PAL]
other names :
[phenylalanine ammonia lyase; Phenylalanine ammonia-lyase]
other gene names :
[PAL1]
uniprot entry name :
A0A0A7AAW9_FLAVE
reactivity :
General
sequence length :
724
storage stability :
Shipped and store at 4 degree C for 6 months.
tested application :
Functional Assay
products description :
Background/Introduction: p65 (RelA) is one of the five members of NF-kappaB transcription factor family that forms distinct transcriptionally active homoand heterodimeric complexes with other members of the family. p65 subunit of NF-kappaB is an important regulator of inflammation, proliferation, and apoptosis. p65 consists of a conserved 300 amino acid long amino-terminal Rel homology domain (RHD), and sequences within the RHD are required for dimerization, DNA binding, interaction with IkappaBs, as well as nuclear translocation. The canonical p65/p50 heterodimer is primarily associated with IkappaBalpha and rapid, stimulus-induced degradation of IkappaBalpha is critical for nuclear translocation and DNA binding of NF-kappaB p65/p50. Over expression of p65 increases endogenous IkappaB protein in both carcinoma and lymphoid cells by two mechanisms: protein stabilization and increased transcription of IkappaB mRNA. p65 plays a key role in Treg biology, which may be of critical importance as therapeutic agents that impact upon NF-kappaB are increasingly considered for the treatment of a diverse spectrum of diseases.
ncbi gi num :
568261083
ncbi acc num :
AHD25301.1
ncbi mol weight :
78,095 Da
size1 :
100 Assays
price1 :
360 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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