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Na+/K+ ATPase Microplate Assay Kit

MBS8243226

100 Assays

285 USD

Assay Kit

Na+/K+ ATPase Microplate Assay Kit

[Na+/K+ ATPase]

[EC 3.6.3.9; Sodium/potassium-exchanging ATPase; Na(+)/K(+)-ATPase; Na(+)/K(+)-exchanging ATPase; Na,K-activated ATPase; Sodium pump; Sodium/potassium-transporting ATPase]

General

Shipped and store at 4 degree C for 6 months.

Functional Assay

Typical Testing Data/Standard Curve (for reference only)

Intra-assay Precision: Intra-assay precision was determined by assaying 24 replicates of three buffer controls containing human MPO in a single assay. Inter-assay Precision: Inter-assay precision was determined by measuring buffer controls of varying human MPO concentrations in multiple assays over several days.

Background/Introduction: Myeloperoxidase (MPO) is synthesized as a single chain precursor, which is then processed into a tetramer consisting of 2 light chains and 2 heavy chains. In response to microbial invasion, MPO is released from the cytoplasmic granules of neutrophils into the extracellular space and phagosome, where it generates hypohalous acids that have a strong microbicidal effect3. Since myeloperoxidase is a major component of myeloid precursor cells, the enzymatic activity of MPO is used to classify acute leukemias4. Myeloperoxidase is used also as a marker of airway inflammation caused either by disease, such as asthma5-6, or environmental irritants7. In addition to the protein itself, autoantibodies against MPO are markers for several systemic vasculitis diseases8.

100 Assays

285 USD