catalog number :
MBS8242741
products full name :
Anti-TRB1 Antibody
products short name :
[TRB1]
products name syn :
[Taste receptor type 2 member 14; T2R14; Taste receptor family B member 1; TRB1]
other names :
[Taste receptor type 2 member 14; Taste receptor type 2 member 14; taste receptor type 2 member 14; taste 2 receptor member 14; Taste receptor family B member 1; TRB1]
products gene name :
[TAS2R14]
other gene names :
[TAS2R14; TAS2R14; TRB1; T2R14; T2R14; TRB1]
uniprot entry name :
T2R14_HUMAN
reactivity :
Human, Mouse
specificity :
Recognizes endogenous levels of TRB1 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
storage stability :
Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
Western Blot: (1/500 - 1/1000). Immunofluorescence/Immunocytochemistry: (1/100 - 1/500)
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TRB1. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to TRB1
ncbi pathways :
Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway (1269573); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543); Taste Transduction Pathway (83088); Taste Transduction Pathway (499)
ncbi summary :
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
uniprot summary :
TAS2R14: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family. Protein type: GPCR, T2R family; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: integral to membrane; plasma membrane. Molecular Function: bitter taste receptor activity; taste receptor activity. Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; G-protein coupled receptor protein signaling pathway