product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-GPR40 Antibody
catalog :
MBS8242645
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of GPR40 expression in K562 (A), mouse kidney (B), COS7 (C) whole cell lysates.
product information
catalog number :
MBS8242645
products type :
Antibody
products full name :
Anti-GPR40 Antibody
products short name :
[GPR40]
products name syn :
[GPR40; Free fatty acid receptor 1; G-protein coupled receptor 40]
other names :
[Free fatty acid receptor 1; Free fatty acid receptor 1; free fatty acid receptor 1; free fatty acid receptor 1; G-protein coupled receptor 40]
products gene name :
[FFAR1]
other gene names :
[FFAR1; FFAR1; FFA1R; GPR40; GPCR40; GPR40]
uniprot entry name :
FFAR1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Monkey
sequence length :
300
specificity :
Recognizes endogenous levels of GPR40 protein.
purity :
The antibody was purified by affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87%, Sodium Chloride, pH 7.3, 30% glycerol, and 0.1% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
Western Blot: (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR40. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to GPR40
ncbi gi num :
3122157
ncbi acc num :
O14842.1
uniprot acc num :
O14842
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Fatty Acids Bound To GPR40 (FFAR1) Regulate Insulin Secretion Pathway (1270106); Free Fatty Acid Receptors Pathway (1269569); Free Fatty Acids Regulate Insulin Secretion Pathway (1270105); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1269592); Incretin Synthesis, Secretion, And Inactivation Pathway (1268750)
ncbi summary :
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009]
uniprot summary :
FFAR1: Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G- proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway. Belongs to the G-protein coupled receptor 1 family. Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: bioactive lipid receptor activity; G-protein coupled receptor activity; guanyl-nucleotide exchange factor activity; lipid binding. Biological Process: energy reserve metabolic process; G-protein coupled receptor protein signaling pathway; glucose homeostasis; insulin secretion; positive regulation of calcium ion transport; positive regulation of GTPase activity; positive regulation of insulin secretion; regulation of insulin secretion
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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