product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-CD74 Antibody
catalog :
MBS8242406
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS8242406 image 1
Western blot analysis of CD74 expression in Ramos (A), Raji (B), PC12 (C) whole cell lysates.
product information
catalog number :
MBS8242406
products type :
Antibody
products full name :
Anti-CD74 Antibody
products short name :
[CD74]
products name syn :
[DHLAG; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74]
other names :
[HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen gamma chain; CD74 molecule; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD_antigen: CD74]
products gene name :
[CD74]
other gene names :
[CD74; CD74; II; DHLAG; HLADG; Ia-GAMMA; DHLAG; Ii]
uniprot entry name :
HG2A_HUMAN
clonality :
Polyclonal
host :
unknown
reactivity :
Human, Rat
sequence length :
296
specificity :
Recognizes endogenous levels of CD74 protein.
purity :
The antibody was purified by affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
Western Blot: (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD74. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to CD74
ncbi gi num :
20178292
ncbi acc num :
P04233.3
uniprot acc num :
P04233
ncbi pathways :
Adaptive Immune System Pathway (1269171); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Hemostasis Pathway (1269340); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Immune System Pathway (1269170); MHC Class II Antigen Presentation Pathway (1269200); Tuberculosis Pathway (213780)
ncbi summary :
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
uniprot summary :
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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