Anti-CD210a Antibody | MyBioSource MBS8242150 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-CD210a Antibody

catalog :

MBS8242150

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of CD210a expression in HuvEc (A), HEK293T (B) whole cell lysates.

image 2 :

Immunofluorescent analysis of CD210a staining in HuvEc cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

product information

catalog number :

MBS8242150

products type :

Antibody

products full name :

Anti-CD210a Antibody

products short name :

[CD210a]

products name syn :

[IL10R; Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD210]

other names :

[Interleukin-10 receptor subunit alpha; Interleukin-10 receptor subunit alpha; interleukin-10 receptor subunit alpha; interleukin 10 receptor subunit alpha; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD_antigen: CD210]

products gene name :

[IL10RA]

other gene names :

[IL10RA; IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R1]

uniprot entry name :

I10R1_HUMAN

clonality :

Polyclonal

host :

unknown

reactivity :

Human, Mouse

sequence length :

578

specificity :

Recognizes endogenous levels of CD210a protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.

storage stability :

Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

tested application :

WB, IF, IC

app notes :

Western Blot: (1/500 - 1/1000); Immunofluorescence/Immunocytochemistry: (1/100 - 1/500)

image1 heading :

Western Blot (WB)

image2 heading :

Immunofluorescence (IF)

other info1 :

Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD210a. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to CD210a

ncbi gi num :

322510034

ncbi acc num :

Q13651.2

uniprot acc num :

Q13651

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Toxoplasmosis Pathway (169642); Toxoplasmosis Pathway (169493); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

ncbi summary :

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]

uniprot summary :

IL10RA: a receptor for interleukin 10 structurally related to interferon receptors. Mediates the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: 11q23. Cellular Component: integral to membrane; plasma membrane. Molecular Function: interleukin-10 binding; interleukin-10 receptor activity; protein binding; receptor activity; signal transducer activity. Biological Process: cytokine and chemokine mediated signaling pathway; response to lipopolysaccharide. Disease: Inflammatory Bowel Disease 28, Autosomal Recessive

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage