product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-PRKD2 Antibody
catalog :
MBS8242032
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of PRKD2 expression in HEK293T (A), Hela (B), NIH3T3 (C) whole cell lysates.
image 2 :
Immunohistochemical analysis of PRKD2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8242032
products type :
Antibody
products full name :
Anti-PRKD2 Antibody
products short name :
[PRKD2]
products name syn :
[PKD2; Serine/threonine-protein kinase D2; nPKC-D2]
other names :
[Serine/threonine-protein kinase D2; Serine/threonine-protein kinase D2; serine/threonine-protein kinase D2; protein kinase D2; nPKC-D2]
products gene name :
[PRKD2]
other gene names :
[PRKD2; PRKD2; PKD2; HSPC187; nPKC-D2; PKD2]
uniprot entry name :
KPCD2_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
878
specificity :
Recognizes endogenous levels of PRKD2 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
storage stability :
Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PRKD2. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to PRKD2
ncbi gi num :
296434570
ncbi acc num :
Q9BZL6.2
uniprot acc num :
Q9BZL6
ncbi pathways :
Aldosterone Synthesis And Secretion Pathway (1272485); Aldosterone Synthesis And Secretion Pathway (1285075); Rap1 Signaling Pathway (868086); Rap1 Signaling Pathway (878042)
ncbi summary :
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
PRKD2: a calcium-independent, phospholipid-dependent CAMK kinase of the PKD family. Activated by diacylglycerol and phorbol esters. may play a role in carcinoid tumor progression. Protein type: EC 2.7.11.13; Kinase, protein; Motility/polarity/chemotaxis; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; PKD family. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm; nucleus; plasma membrane. Molecular Function: ATP binding; metal ion binding; protein binding; protein kinase activity; protein kinase C activity; protein serine/threonine kinase activity. Biological Process: activation of CREB transcription factor; activation of NF-kappaB transcription factor; adaptive immune response; angiogenesis; cell adhesion; cell death; peptidyl-serine phosphorylation; positive regulation of angiogenesis; positive regulation of blood vessel endothelial cell migration; positive regulation of cell adhesion; positive regulation of endothelial cell proliferation; positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of interleukin-2 production; positive regulation of interleukin-8 production; positive regulation of peptidyl-serine phosphorylation; positive regulation of T cell receptor signaling pathway; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein amino acid autophosphorylation; protein amino acid phosphorylation; T cell receptor signaling pathway; vascular endothelial growth factor receptor signaling pathway
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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