product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-TUFM Antibody
catalog :
MBS8241844
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of TUFM expression in H1299 (A), A431 (B), NIH3T3 (C) whole cell lysates.
image 2 :
Immunohistochemical analysis of TUFM staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8241844
products type :
Antibody
products full name :
Anti-TUFM Antibody
products short name :
[TUFM]
products name syn :
[Elongation factor Tu, mitochondrial; EF-Tu; P43]
other names :
[Elongation factor Tu, mitochondrial; Elongation factor Tu, mitochondrial; elongation factor Tu, mitochondrial; Tu translation elongation factor, mitochondrial; P43]
products gene name :
[TUFM]
other gene names :
[TUFM; TUFM; P43; EFTU; COXPD4; EF-TuMT; EF-Tu]
uniprot entry name :
EFTU_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Bovine, Dog, Monkey, Pig
sequence length :
452
specificity :
Recognizes endogenous levels of TUFM protein.
purity :
The antibody was purified by affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TUFM. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to TUFM
ncbi gi num :
1706611
ncbi acc num :
P49411.2
uniprot acc num :
P49411
ncbi pathways :
Mitochondrial Translation Pathway (1268842); Mitochondrial Translation Elongation Pathway (1268844); Organelle Biogenesis And Maintenance Pathway (1268838)
ncbi summary :
This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]
uniprot summary :
EFTU: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Defects in TUFM are the cause of combined oxidative phosphorylation deficiency type 4 (COXPD4). COXPD4 is characterized by neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes. Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. Protein type: Translation elongation; RNA-binding; Translation; Mitochondrial. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: membrane; mitochondrion. Molecular Function: GTP binding; GTPase activity; protein binding; translation elongation factor activity. Biological Process: mitochondrial translation; organelle organization and biogenesis; translational elongation. Disease: Combined Oxidative Phosphorylation Deficiency 4
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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