catalog number :
MBS8241635
products full name :
Anti-KCNK9 Antibody
products short name :
[KCNK9]
products name syn :
[TASK3; Potassium channel subfamily K member 9; Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2]
other names :
[Potassium channel subfamily K member 9; Potassium channel subfamily K member 9; potassium channel subfamily K member 9; potassium two pore domain channel subfamily K member 9; Acid-sensitive potassium channel protein TASK-3; TWIK-related acid-sensitive K(+) channel 3; Two pore potassium channel KT3.2; Two pore K(+) channel KT3.2]
products gene name :
[KCNK9]
other gene names :
[KCNK9; KCNK9; KT3.2; TASK3; K2p9.1; TASK-3; TASK3; Two pore K(+) channel KT3.2]
uniprot entry name :
KCNK9_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of KCNK9 protein.
purity :
The antibody was purified by affinity chromatography.
form :
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
storage stability :
Ships on blue ice. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western Blot: (1/1000 - 1/2000); Immunohistochemistry: (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence of human KCNK9. The exact sequence is proprietary.
products description :
Rabbit polyclonal to KCNK9
ncbi pathways :
Aldosterone Synthesis And Secretion Pathway (1272485); Aldosterone Synthesis And Secretion Pathway (1285075); Cardiac Conduction Pathway (1339115); Muscle Contraction Pathway (1269868); Neuronal System Pathway (1268763); Nicotine Activity On Dopaminergic Neurons Pathway (198858); Phase 4 - Resting Membrane Potential Pathway (1339116); Potassium Channels Pathway (1268821); TWIK-releated Acid-sensitive K+ Channel (TASK) Pathway (1268834); Tandem Pore Domain Potassium Channels Pathway (1268831)
ncbi summary :
This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
uniprot summary :
KCNK9: pH-dependent, voltage-insensitive, background potassium channel protein. Mainly found in the cerebellum. Also found in adrenal gland, kidney and lung. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 8q24.3. Cellular Component: integral to plasma membrane; plasma membrane; synaptic vesicle. Molecular Function: potassium ion leak channel activity; protein heterodimerization activity; protein homodimerization activity; voltage-gated potassium channel activity. Biological Process: potassium ion transport; stabilization of membrane potential; synaptic transmission. Disease: Birk-barel Mental Retardation Dysmorphism Syndrome