catalog number :
MBS8241620
products full name :
Anti-NT5C1A Antibody
products short name :
[NT5C1A]
products name syn :
[Cytosolic 5'-nucleotidase 1A; cN1A; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA]
other names :
[Cytosolic 5'-nucleotidase 1A; Cytosolic 5'-nucleotidase 1A; cytosolic 5'-nucleotidase 1A; 5'-nucleotidase, cytosolic IA; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA]
products gene name :
[NT5C1A]
other gene names :
[NT5C1A; NT5C1A; CN1; CNI; CN-I; CN1A; CN-IA; cN1A; cN-I; cN-IA]
uniprot entry name :
5NT1A_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of NT5C1A protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
app notes :
Western Blot: (1/500 - 1/1000); Immunofluorescence/Immunocytochemistry: (1/100 - 1/500)
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NT5C1A. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to NT5C1A
ncbi mol weight :
41,021 Da
ncbi pathways :
Integrated Pancreatic Cancer Pathway (711360); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Nucleotides Pathway (1270133); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Purine Catabolism Pathway (1270137); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (1270134); Purine Metabolism Pathway (307)
ncbi summary :
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
uniprot summary :
NT5C1A: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia. Belongs to the 5'-nucleotidase type 3 family. Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 3.1.3.5; Phosphatase (non-protein). Chromosomal Location of Human Ortholog: 1p34.3-p33. Cellular Component: cytosol. Molecular Function: 5'-nucleotidase activity; magnesium ion binding; nucleotide binding. Biological Process: adenosine metabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; nucleoside metabolic process; purine base metabolic process; purine nucleoside monophosphate catabolic process; purine nucleotide catabolic process; pyrimidine base metabolic process; pyrimidine nucleoside catabolic process