product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-KCNK10 Antibody
catalog :
MBS8241606
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of KCNK10 expression in Jurkat (A), mouse brain (B), rat brain (C) whole cell lysates.
image 2 :
Immunohistochemical analysis of KCNK10 staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8241606
products type :
Antibody
products full name :
Anti-KCNK10 Antibody
products short name :
[KCNK10]
products name syn :
[TREK2; Potassium channel subfamily K member 10; Outward rectifying potassium channel protein TREK-2; TREK-2 K(+) channel subunit]
other names :
[Potassium channel subfamily K member 10; Potassium channel subfamily K member 10; potassium channel subfamily K member 10; potassium two pore domain channel subfamily K member 10; Outward rectifying potassium channel protein TREK-2; TREK-2 K(+) channel subunit]
products gene name :
[KCNK10]
other gene names :
[KCNK10; KCNK10; TREK2; TREK-2; K2p10.1; PPP1R97; TREK2]
uniprot entry name :
KCNKA_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
538
specificity :
Recognizes endogenous levels of KCNK10 protein.
purity :
The antibody was purified by affinity chromatography.
form :
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western Blot: (1/1000 - 1/2000); Immunohistochemistry: (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence of human KCNK10. The exact sequence is proprietary. Source: Rabbit
products description :
Rabbit polyclonal to KCNK10
ncbi gi num :
13431412
ncbi acc num :
P57789.1
uniprot acc num :
P57789
ncbi pathways :
Cardiac Conduction Pathway (1339115); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Muscle Contraction Pathway (1269868); Neuronal System Pathway (1268763); Phase 4 - Resting Membrane Potential Pathway (1339116); Potassium Channels Pathway (1268821); TWIK Related Potassium Channel (TREK) Pathway (1268833); Tandem Pore Domain Potassium Channels Pathway (1268831)
ncbi summary :
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]
uniprot summary :
TREK-2: Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 14q31.3. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: potassium channel activity; potassium ion leak channel activity; voltage-gated ion channel activity. Biological Process: memory; signal transduction; stabilization of membrane potential; synaptic transmission; transport
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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