Anti-TACSTD2 Antibody | MyBioSource MBS8240344 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-TACSTD2 Antibody

catalog :

MBS8240344

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of TACSTD2 expression in human prostate (A), NIH3T3 (B) whole cell lysates.

image 2 :

Immunohistochemical analysis of TACSTD2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

image 3 :

Immunofluorescent analysis of TACSTD2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

product information

catalog number :

MBS8240344

products type :

Antibody

products full name :

Anti-TACSTD2 Antibody

products short name :

[TACSTD2]

products name syn :

[GA733-1; M1S1; TROP2; Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1]

other names :

[tumor-associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1]

products gene name :

[TACSTD2]

other gene names :

[TACSTD2; TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; GA733-1; M1S1; TROP2]

uniprot entry name :

TACD2_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse, Rat, Porcine

sequence length :

323

specificity :

Recognizes endogenous levels of TACSTD2 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB),Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

app notes :

WB (1/500 - 1/1000). IHC (1/100 - 1/200). IF/IC (1/100 - 1/500)

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunofluorescence (IF)

other info1 :

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TACSTD2. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to TACSTD2

ncbi gi num :

166795236

ncbi acc num :

NP_002344.2

ncbi gb acc num :

NM_002353.2

uniprot acc num :

P09758

ncbi summary :

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]

uniprot summary :

TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1p32. Cellular Component: extracellular space; membrane; integral to plasma membrane; basal plasma membrane; nucleus; cytosol; lateral plasma membrane. Molecular Function: protein binding; receptor activity. Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation; visual perception; regulation of epithelial cell proliferation. Disease: Corneal Dystrophy, Gelatinous Drop-like

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage