catalog number :
MBS823810
products type :
Blocking Peptide
products full name :
CD70 Blocking Peptide
products short name :
[CD70]
products name syn :
[CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD70]
other names :
[CD70 antigen; CD70 antigen; CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD70 molecule; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70]
products gene name :
[CD70]
other gene names :
[CD70; CD70; CD27L; CD27LG; TNFSF7; CD27L; CD27LG; TNFSF7; CD27-L]
uniprot entry name :
CD70_HUMAN
form :
Lyophilized powder
storage stability :
Shipped at 4 degree C. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info1 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
other info2 :
SwissProt: P49327 (Human)
products description :
The peptide is used to block Anti-CD70 Antibody reactivity.
ncbi acc num :
NP_001243.1
ncbi gb acc num :
NM_001252.4
ncbi mol weight :
23,438 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460)
ncbi summary :
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
uniprot summary :
CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family. Protein type: Cytokine; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13. Cellular Component: extracellular space; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding. Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction