product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-FOXD3 Antibody
catalog :
MBS8236299
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of FOXD3 expression in Jurkat (A), K562 (B), NIH3T3 (C) whole cell lysates.
image 2 :
Immunohistochemical analysis of FOXD3 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8236299
products type :
Antibody
products full name :
Anti-FOXD3 Antibody
products short name :
[FOXD3]
products name syn :
[HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis]
other names :
[forkhead box protein D3; Forkhead box protein D3; forkhead box protein D3; forkhead box D3; HNF3/FH transcription factor genesis]
products gene name :
[FOXD3]
other gene names :
[FOXD3; FOXD3; AIS1; HFH2; VAMAS2; Genesis; HFH2]
uniprot entry name :
FOXD3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Chicken
sequence length :
478
specificity :
Recognizes endogenous levels of FOXD3 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB (1/500 - 1/1000). IHC (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FOXD3. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to FOXD3
ncbi gi num :
6912372
ncbi acc num :
NP_036315.1
ncbi gb acc num :
NM_012183.2
uniprot acc num :
Q9UJU5
ncbi pathways :
Developmental Biology Pathway (1270302); Neural Crest Differentiation Pathway (672460); POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway (1270347); Transcriptional Regulation Of Pluripotent Stem Cells Pathway (1270346); Wnt Signaling Pathway And Pluripotency (198847)
ncbi summary :
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. [provided by RefSeq, Nov 2008]
uniprot summary :
FOXD3: Binds to the consensus sequence 5 -A[AT]T[AG]TTTGTTT-3 and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 1p31.3. Cellular Component: nucleoplasm; nuclear chromatin. Molecular Function: protein binding; double-stranded DNA binding; transcription factor activity. Biological Process: embryonic placenta development; transcription, DNA-dependent; in utero embryonic development; somatic stem cell maintenance; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; trophectodermal cell differentiation. Disease: Autoimmune Disease, Susceptibility To, 1
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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