catalog number :
MBS823537
products type :
Blocking Peptide
products full name :
Somatostatin Blocking Peptide
products short name :
[Somatostatin]
products name syn :
[Somatostatin; Growth hormone release-inhibiting factor]
other names :
[somatostatin preproprotein; Somatostatin; somatostatin; somatostatin-14; somatostatin-28; prepro-somatostatin; growth hormone release-inhibiting factor; somatostatin; Growth hormone release-inhibiting factorCleaved into the following 2 chains:Somatostatin-28; Somatostatin-14]
products gene name :
[SST]
other gene names :
[SST; SST; SMST]
uniprot entry name :
SMS_HUMAN
reactivity :
Human, Mouse, Rat, Bovine, Chicken, Monkey, Pig, Sheep
form :
Lyophilized powder
storage stability :
Shipped at 4 degree C. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info1 :
Source: Synthetic. Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-Somatostatin Antibody reactivity.
ncbi acc num :
NP_001039.1
ncbi gb acc num :
NM_001048.3
ncbi mol weight :
12,736 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Peptide Ligand-binding Receptors Pathway (106358); SIDS Susceptibility Pathways (198901); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
uniprot summary :
SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family. Protein type: Secreted, signal peptide; Hormone; Secreted. Chromosomal Location of Human Ortholog: 3q28. Cellular Component: extracellular space; cell soma; extracellular region. Molecular Function: hormone activity. Biological Process: response to drug; negative regulation of cell proliferation; synaptic transmission; G-protein coupled receptor protein signaling pathway; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; induction of apoptosis by hormones; response to heat; response to steroid hormone stimulus; digestion; response to amino acid stimulus; regulation of cell migration; response to nutrient