Anti-MFG-E8 Antibody | MyBioSource MBS8234163 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-MFG-E8 Antibody

catalog :

MBS8234163

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of MFG-E8 expression in A549 (A), NS-1 (B), PC12 (C) whole cell lysates.

product information

catalog number :

MBS8234163

products type :

Antibody

products full name :

Anti-MFG-E8 Antibody

products short name :

[MFG-E8]

products name syn :

[Lactadherin; Breast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8; SED1]

other names :

[lactadherin isoform b; Lactadherin; lactadherin; milk fat globule-EGF factor 8 protein; Breast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8]

products gene name :

[MFGE8]

other gene names :

[MFGE8; MFGE8; BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888; MFG-E8]

uniprot entry name :

MFGM_HUMAN

clonality :

Polyclonal

host :

unknown

reactivity :

Human, Mouse, Rat

sequence length :

335

specificity :

Recognizes endogenous levels of MFG-E8 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB)

app notes :

WB (1/500 - 1/1000)

image1 heading :

Western Blot (WB)

other info1 :

Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MFG-E8. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to MFG-E8

ncbi gi num :

167830477

ncbi acc num :

NP_001108086.1

ncbi gb acc num :

NM_001114614.2

uniprot acc num :

Q08431

ncbi mol weight :

37,523 Da

ncbi pathways :

Amyloids Pathway (1269169); Disease Pathway (1268854); Integrins In Angiogenesis Pathway (137999)

ncbi summary :

This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

uniprot summary :

MFGE8: Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 15q25. Cellular Component: extrinsic to plasma membrane; extracellular matrix; extracellular space; membrane; extracellular region; vesicle; external side of plasma membrane. Molecular Function: integrin binding; phosphatidylethanolamine binding; phosphatidylserine binding. Biological Process: viral reproduction; single fertilization; phagocytosis, recognition; angiogenesis; cell adhesion; phagocytosis, engulfment

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage

company information

MyBioSource

P.O. Box 153308
San Diego, CA 92195-3308

sales@mybiosource.com

https://www.mybiosource.com

1-888-627-0165

headquarters: USA

MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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