catalog number :
MBS8233661
products full name :
HNRNPA3 siRNA (Human)
products short name :
[HNRNPA3]
products name syn :
[HNRPA3; Heterogeneous nuclear ribonucleoprotein A3; hnRNP A3]
other names :
[heterogeneous nuclear ribonucleoprotein A3; Heterogeneous nuclear ribonucleoprotein A3; heterogeneous nuclear ribonucleoprotein A3; heterogeneous nuclear ribonucleoprotein A3]
products gene name :
[HNRNPA3]
other gene names :
[HNRNPA3; HNRNPA3; FBRNP; HNRPA3; D10S102; 2610510D13Rik; HNRPA3; hnRNP A3]
uniprot entry name :
ROA3_HUMAN
specificity :
HNRNPA3 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
form :
Lyophilized powder
storage stability :
Shipped at 4°C. Store at -20°C for one year.
tested application :
RNA Interference (RNAi)
other info1 :
Source: Synthetic
other info2 :
Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency. Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well). Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human HNRNPA3 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
products description :
siRNA to inhibit HNRNPA3 expression using RNA interference
ncbi acc num :
NP_919223.1
ncbi gb acc num :
NM_194247.2
ncbi mol weight :
37,029 Da
ncbi pathways :
Gene Expression Pathway (1269649); Processing Of Capped Intron-Containing Pre-mRNA Pathway (1269688); Spliceosome Pathway (125136); Spliceosome Pathway (124832); MRNA Splicing Pathway (1269689); MRNA Splicing - Major Pathway (1269690)
uniprot summary :
hnRNP A3: Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing. 2 isoforms of the human protein are produced by alternative splicing. Protein type: RNA splicing; RNA-binding; Spliceosome. Chromosomal Location of Human Ortholog: 2q31.2. Cellular Component: nucleoplasm; nucleus; ribonucleoprotein complex. Molecular Function: protein binding; RNA binding; nucleotide binding. Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression