catalog number :
MBS823357
products type :
Blocking Peptide
products full name :
Cytokeratin 19 Blocking Peptide
products short name :
[Cytokeratin 19]
products name syn :
[Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19]
other names :
[keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 19; keratin, type I cytoskeletal 19; CK-19; keratin-19; cytokeratin 19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament; keratin 19; Cytokeratin-19; CK-19; Keratin-19; K19]
products gene name :
[KRT19]
other gene names :
[KRT19; KRT19; K19; CK19; K1CS; CK-19; K19]
uniprot entry name :
K1C19_HUMAN
form :
Lyophilized powder
storage stability :
Shipped at 4°C. Store at -20°C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.
other info1 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-Cytokeratin 19 Antibody (Catalog# MBS822263) reactivity.
ncbi acc num :
NP_002267.2
ncbi gb acc num :
NM_002276.4
ncbi pathways :
Signaling Mediated By P38-alpha And P38-beta Pathway (138012)
ncbi summary :
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
uniprot summary :
K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: dystrophin-associated glycoprotein complex; costamere; intermediate filament; Z disc; sarcolemma. Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; protein complex binding. Biological Process: viral reproduction; response to estrogen stimulus; sarcomere organization