catalog number :
MBS823225
products type :
Blocking Peptide
products full name :
CD102 Blocking Peptide
products short name :
[CD102]
products name syn :
[Intercellular adhesion molecule 2; ICAM-2; CD102]
other names :
[intercellular adhesion molecule 2; Intercellular adhesion molecule 2; intercellular adhesion molecule 2; ICAM-2; intercellular adhesion molecule 2; CD_antigen: CD102]
products gene name :
[ICAM2]
other gene names :
[ICAM2; ICAM2; CD102; ICAM-2]
uniprot entry name :
ICAM2_HUMAN
reactivity :
Human, Mouse, Rat
form :
Lyophilized powder
storage stability :
Ships on blue ice. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info1 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-CD102 Antibody reactivity.
ncbi acc num :
NP_000864.2
ncbi gb acc num :
NM_000873.3
ncbi pathways :
Adaptive Immune System Pathway (366160); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Extracellular Matrix Organization Pathway (576262); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413); Integrin Cell Surface Interactions Pathway (106110); Natural Killer Cell Mediated Cytotoxicity Pathway (83079); Natural Killer Cell Mediated Cytotoxicity Pathway (490); Amb2 Integrin Signaling Pathway (137945)
ncbi summary :
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 17q23.3. Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod. Molecular Function: integrin binding. Biological Process: cell-cell adhesion; extracellular matrix organization and biogenesis; regulation of immune response; cell adhesion