catalog number :
MBS822959
products type :
Blocking Peptide
products full name :
BACH1 Blocking Peptide
products short name :
[BACH1]
products name syn :
[Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303]
other names :
[transcription regulator protein BACH1; Transcription regulator protein BACH1; transcription regulator protein BACH1; basic region leucine zipper transcriptional regulator BACH1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; BTB and CNC homolog 1; HA2303]
products gene name :
[BACH1]
other gene names :
[BACH1; BACH1; BACH-1; BTBD24]
uniprot entry name :
BACH1_HUMAN
reactivity :
Human, Monkey
form :
Lyophilized powder
storage stability :
Shipped at 4 degree C. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info1 :
Source: Synthetic. Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-BACH1 Antibody reactivity.
ncbi acc num :
NP_001177.1
ncbi gb acc num :
NM_001186.3
ncbi mol weight :
81,958 Da
ncbi pathways :
Integrated Breast Cancer Pathway (219801)
ncbi summary :
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]
uniprot summary :
BACH1: a transcriptional regulator that acts as a repressor or activator. Binds, in-vitro, to NF-E2 binding sites on DNA. Plays an important role in coordinating transcription activation and repression by NF-E2. Belongs to the bZIP family, CNC subfamily. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 21q22.11. Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus. Molecular Function: heme binding; transcription factor activity. Biological Process: G1/S-specific transcription in mitotic cell cycle; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; G2/M-specific transcription in mitotic cell cycle