catalog number :
MBS822924
products type :
Blocking Peptide
products full name :
NPY2R Blocking Peptide
products short name :
[NPY2R]
products name syn :
[Neuropeptide Y receptor type 2; NPY2-R; NPY-Y2 receptor; Y2 receptor]
other names :
[neuropeptide Y receptor type 2; Neuropeptide Y receptor type 2; neuropeptide Y receptor type 2; Y2 receptor; NPY-Y2 receptor; neuropeptide Y receptor Y2; NPY-Y2 receptor; Y2 receptor]
products gene name :
[NPY2R]
other gene names :
[NPY2R; NPY2R; NPY2-R; NPY2-R; Y2 receptor]
uniprot entry name :
NPY2R_HUMAN
form :
Lyophilized powder
storage stability :
Shipped at 4 degree C. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info1 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
products description :
The peptide is used to block Anti-NPY2R Antibody reactivity.
ncbi acc num :
NP_000901.1
ncbi gb acc num :
NM_000910.2
ncbi mol weight :
42,731 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Peptide GPCRs Pathway (198897); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114)
uniprot summary :
NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY NPY PYY (3-36) NPY (2-36) [Ile-31, Gln-34] PP [Leu- 31, Pro-34] NPY PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q31. Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane. Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity. Biological Process: positive regulation of dopamine secretion; secretion; behavioral fear response; positive regulation of cell adhesion; negative regulation of synaptic transmission, glutamatergic; locomotory behavior; positive regulation of peptide secretion; elevation of cytosolic calcium ion concentration; negative regulation of cAMP biosynthetic process; neuropeptide signaling pathway; negative regulation of secretion; positive regulation of smooth muscle contraction; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of sensory perception of pain; negative regulation of neurological process; positive regulation of circadian sleep/wake cycle, non-REM sleep; nitric oxide mediated signal transduction