product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Cathepsin H Antibody
catalog :
MBS8229166
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of Cathepsin H expression in Jurkat (A), K562 (B), mouse kidney (C), PC12 (D) whole cell lysates.
image 2 :
Immunohistochemical analysis of Cathepsin H staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS8229166
products type :
Antibody
products full name :
Anti-Cathepsin H Antibody
products short name :
[Cathepsin H]
products name syn :
[CPSB; Pro-cathepsin H]
other names :
[pro-cathepsin H preproprotein; Pro-cathepsin H; pro-cathepsin H; cathepsin H]
products gene name :
[CTSH]
other gene names :
[CTSH; CTSH; ACC4; ACC5; CPSB; ACC-4; ACC-5; minichain; CPSB]
uniprot entry name :
CATH_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
335
specificity :
Recognizes endogenous levels of Cathepsin H protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB (1/500 - 1/1000), IHC (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cathepsin H. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to Cathepsin H
ncbi gi num :
23110955
ncbi acc num :
NP_004381.2
ncbi gb acc num :
NM_004390.3
uniprot acc num :
P09668
ncbi mol weight :
37,394 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Immune System Pathway (1269170); Lysosome Pathway (99052); Lysosome Pathway (96865); MHC Class II Antigen Presentation Pathway (1269200)
ncbi summary :
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq, Mar 2010]
uniprot summary :
CTSH: Important for the overall degradation of proteins in lysosomes. Belongs to the peptidase C1 family. Protein type: EC 3.4.22.16; Protease. Chromosomal Location of Human Ortholog: 15q25.1. Cellular Component: extracellular space; lysosome; acrosome; cytosol; outer dense fiber. Molecular Function: peptidase activity; protein binding; HLA-A specific activating MHC class I receptor activity; protein self-association; serine-type endopeptidase activity; cysteine-type endopeptidase activity; endopeptidase activity; protein complex binding; caspase activator activity; aminopeptidase activity; kininogen binding; cysteine-type peptidase activity. Biological Process: caspase activation; adaptive immune response; response to retinoic acid; protein destabilization; membrane protein proteolysis; proteolysis; antigen processing and presentation; positive regulation of angiogenesis; positive regulation of cell proliferation; zymogen activation; spermatogenesis; metanephros development; surfactant homeostasis; immune response-regulating signal transduction; T cell mediated cytotoxicity; negative regulation of apoptosis; positive regulation of cell migration
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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