protein

IL-28RA Blocking Peptide

MBS822916

1 mg

160 USD

Blocking Peptide

IL-28RA Blocking Peptide

[IL-28RA]

[IL28RA; LICR2; Interferon lambda receptor 1; IFN-lambda receptor 1; IFN-lambda-R1; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Likely interleukin or cytokine receptor 2; LICR2]

[interferon lambda receptor 1 isoform 1; Interferon lambda receptor 1; interferon lambda receptor 1; CRF2-12; IL-28RA; IL-28R-alpha; IFN-lambda-R1; IFN-lambda receptor 1; interleukin 28 receptor A; IL-28 receptor subunit alpha; interferon lambda, receptor 1; interleukin 28 alpha receptor; class II cytokine receptor CRF2/12; interleukin or cytokine receptor 2; cytokine receptor class-II member 12; cytokine receptor family 2 member 12; interleukin-28 receptor subunit alpha; likely interleukin or cytokine receptor 2; interleukin 28 receptor, alpha (interferon, lambda receptor); interferon, lambda receptor 1; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; CRF2-12; Interleukin-28 receptor subunit alpha; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Likely interleukin or cytokine receptor 2; LICR2]

[IL28RA]

[IFNLR1; IFNLR1; IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1; IL28RA; LICR2; IFN-lambda receptor 1; IFN-lambda-R1; CRF2-12; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; LICR2]

INLR1_HUMAN

Human

520

>85%

Lyophilized powder

Shipped at 4 degree C. Store at -20 degree C for one year.

Blocking (BL)

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Source: Synthetic. Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

The peptide is used to block Anti-IL-28RA Antibody reactivity.

25014103

NP_734464.1

NM_170743.3

Q96HI0

27,536 Da

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Type III Interferon Signaling Pathway (755437)

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

IL28RA: The IL28RA/IL10RB dimer is a receptor for IL28A, IL28B and IL29. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the type II cytokine receptor family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1p36.11. Cellular Component: integral to membrane; interleukin-28 receptor complex. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding. Biological Process: negative regulation of cell proliferation; mucosal immune response; cytokine and chemokine mediated signaling pathway; regulation of defense response to virus by host; defense response to virus

1 mg

160 USD

5 mg

305