CD271 Blocking Peptide | MyBioSource MBS822729 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

CD271 Blocking Peptide

catalog :

MBS822729

quantity :

1 mg

price :

160 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS822729

products type :

Blocking Peptide

products full name :

CD271 Blocking Peptide

products short name :

[CD271]

products name syn :

[TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271]

other names :

[tumor necrosis factor receptor superfamily member 16; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; p75 ICD; NGF receptor; TNFR superfamily, member 16; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD_antigen: CD271]

products gene name :

[NGFR]

other gene names :

[NGFR; NGFR; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR; TNFRSF16; NGF receptor]

uniprot entry name :

TNR16_HUMAN

host :

Synthetic

reactivity :

Human, Mouse, Rat, Bovine, Dog, Monkey, Pig

sequence length :

427

purity :

>85%

form :

Lyophilized powder

storage stability :

Shipped at 4°C. Store at -20°C for one year.

tested application :

Blocking (BL)

other info1 :

Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

other info2 :

Directions for use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4°C for overnight or at room temperature for 2 hours.

products description :

The peptide is used to block Anti-CD271 Antibody (MBS822729) reactivity.

ncbi gi num :

4505393

ncbi acc num :

NP_002498.1

ncbi gb acc num :

NM_002507.3

uniprot acc num :

P48448

ncbi pathways :

Axonal Growth Inhibition (RHOA Activation) Pathway (106454); Axonal Growth Stimulation Pathway (106453); BDNF Signaling Pathway (712093); Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (106443); Ceramide Signalling Pathway (106451); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); NADE Modulates Death Signalling Pathway (106446); NF-kB Is Activated And Signals Survival Pathway (106450); NFG And ProNGF Binds To P75NTR Pathway (106442)

ncbi summary :

Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

uniprot summary :

NGFR: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR- associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1. Can form a ternary complex with NTRK1 and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of NGFR and NTRK1. Interacts with NTRK2; may regulate the ligand specificity of the NTRK2 receptor. Interacts with LINGO1. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17q21-q22. Cellular Component: nucleoplasm; cell surface; integral to plasma membrane; plasma membrane; extracellular region; cytosol; endosome. Molecular Function: protein binding; signal transducer activity; transmembrane receptor activity; death receptor activity; ubiquitin protein ligase binding; nerve growth factor binding; receptor activity; Rab GTPase binding. Biological Process: axon guidance; detection of temperature stimulus; hair follicle morphogenesis; membrane protein intracellular domain proteolysis; central nervous system development; nerve growth factor receptor signaling pathway; negative regulation of fibroblast growth factor receptor signaling pathway; positive regulation of apoptosis; positive regulation of odontogenesis of dentine-containing teeth; regulation of caspase activity; regulation of axonogenesis; glucose homeostasis; negative regulation of hair follicle development; negative regulation of cell cycle; intracellular protein transport; positive regulation of fibroblast proliferation; nerve development; positive regulation of axonogenesis; negative regulation of axonogenesis; circadian regulation of gene expression; negative regulation of apoptosis

size1 :

1 mg

price1 :

160 USD

size2 :

5 mg

price2 :

305

more info or order :

MyBioSource product webpage