catalog number :
MBS822675
products type :
Blocking Peptide
products full name :
Aquaporin 5 Blocking Peptide
products short name :
[Aquaporin 5]
products name syn :
[Aquaporin-5; AQP-5]
other names :
[aquaporin-5; Aquaporin-5; aquaporin-5; aquaporin 5]
products gene name :
[AQP5]
other gene names :
[AQP5; AQP5; PPKB; AQP-5; AQP-5]
uniprot entry name :
AQP5_HUMAN
reactivity :
Human, Mouse, Rat
form :
Lyophilized powder
storage stability :
Shipped at 4 degree C. Store at -20 degree C for one year.
tested application :
Blocking (BL)
app notes :
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
other info1 :
Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry. Source: Synthetic
products description :
The peptide is used to block Anti-Aquaporin 5 Antibody reactivity.
ncbi acc num :
NP_001642.1
ncbi gb acc num :
NM_001651.3
ncbi mol weight :
28,292 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (187187); Passive Transport By Aquaporins Pathway (187188); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway (137918); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
uniprot summary :
AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family. Protein type: Membrane protein, multi-pass; Transporter, aquaporin family; Channel, misc.; Membrane protein, integral; Transporter. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: microvillus; integral to plasma membrane; endoplasmic reticulum; apical plasma membrane; plasma membrane; basal plasma membrane. Molecular Function: protein binding; water channel activity; glycerol channel activity. Biological Process: odontogenesis; glycerol transport; camera-type eye morphogenesis; cellular water homeostasis; water transport; carbon dioxide transport; pancreatic juice secretion; excretion; transmembrane transport; saliva secretion