catalog number :
MBS8225422
products full name :
Anti-COX7A2/3 Antibody
products short name :
[COX7A2/3]
products name syn :
[COX7A2P2; COX7A3; COX7AL2; COX7AP2; Putative cytochrome c oxidase subunit 7A3, mitoch ondrial; Cytochrome c oxidase subunit VIIa 3; COX7A2; COX7AL; Cytochrome c oxidase subunit 7A2, mitochondrial; Cytochrome c oxidase subunit VIIa -liver/heart; Cytochrome c]
other names :
[Putative cytochrome c oxidase subunit 7A3, mitochondrial; Putative cytochrome c oxidase subunit 7A3, mitochondrial; cytochrome c oxidase subunit 7A2, mitochondrial; cytochrome c oxidase subunit VIIa polypeptide 2 (liver); Cytochrome c oxidase subunit VIIa 3]
products gene name :
[COX7A2]
products gene name syn :
[COX7A2P2]
other gene names :
[COX7A2; COX7A2P2; VIIAL; COX7AL; COX7AL1; COXVIIAL; COXVIIa-L; COX7A3; COX7AL2; COX7AP2]
uniprot entry name :
COX7S_HUMAN
reactivity :
Human, Mouse, Rat, Bovine, Dog, Monkey, Sheep
specificity :
Recognizes endogenous levels of COX7A2/3 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB (1/500 - 1/1000), IHC (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human COX7A2/3. The exact sequence is proprietary. Gene symbol: COX7A2;COX7A2P2
products description :
Rabbit polyclonal antibody to COX7A2/3
ncbi mol weight :
11,841 Da
ncbi pathways :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Cytochrome C Oxidase Pathway (413434); Cytochrome C Oxidase Pathway (468345); Electron Transport Chain Pathway (198860); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Non-alcoholic Fatty Liver Disease (NAFLD) Pathway (862188)
ncbi summary :
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]
uniprot summary :
COX7A2: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIIa family. Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; EC 1.9.3.1; Oxidoreductase. Chromosomal Location of Human Ortholog: 6q12. Cellular Component: mitochondrial respiratory chain. Molecular Function: cytochrome-c oxidase activity