Anti-Apolipoprotein C2 Antibody | MyBioSource MBS822340 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-Apolipoprotein C2 Antibody

catalog :

MBS822340

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of Apolipoprotein C2 expression in HeLa (A), mouse liver (B), rat liver (C) whole cell lysates.

product information

catalog number :

MBS822340

products type :

Antibody

products full name :

Anti-Apolipoprotein C2 Antibody

products short name :

[Apolipoprotein C2]

products name syn :

[APC2; Apolipoprotein C-II; Apo-CII; ApoC-II, Apolipoprotein C2]

other names :

[apolipoprotein C-II; Apolipoprotein C-II; apolipoprotein C-II; apolipoprotein C2; apolipoprotein C-II; Apolipoprotein C2Cleaved into the following chain:Proapolipoprotein C-II; ProapoC-II]

products gene name :

[APOC2]

other gene names :

[APOC2; APOC2; APO-CII; APOC-II; APC2; Apo-CII; ApoC-II; ProapoC-II]

uniprot entry name :

APOC2_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse, Rat, Monkey

sequence length :

101

specificity :

Recognizes endogenous levels of Apolipoprotein C2 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB)

app notes :

WB (1/500 - 1/1000)

image1 heading :

Western Blot (WB)

other info2 :

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Apolipoprotein C2. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to Apolipoprotein C2

ncbi gi num :

32130518

ncbi acc num :

NP_000474.2

ncbi gb acc num :

NM_000483.4

uniprot acc num :

P02655

ncbi pathways :

Chylomicron-mediated Lipid Transport Pathway (106157); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); HDL-mediated Lipid Transport Pathway (106158); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Retinoid Metabolism And Transport Pathway (187208); Signal Transduction Pathway (477114)

ncbi summary :

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]

uniprot summary :

APOC2: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B). It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Belongs to the apolipoprotein C2 family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: extracellular space; chylomicron; early endosome; extracellular region. Molecular Function: phospholipase binding; protein homodimerization activity; lipase inhibitor activity; lipid binding; phospholipase activator activity. Biological Process: positive regulation of fatty acid biosynthetic process; phototransduction, visible light; negative regulation of cholesterol transport; cholesterol efflux; lipoprotein metabolic process; cholesterol homeostasis; reverse cholesterol transport; phospholipid efflux; negative regulation of catalytic activity; positive regulation of lipoprotein lipase activity; negative regulation of receptor-mediated endocytosis; retinoid metabolic process; negative regulation of lipid metabolic process; lipid catabolic process. Disease: Apolipoprotein C-ii Deficiency

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage