Anti-HSP70 Antibody | MyBioSource MBS8221756 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-HSP70 Antibody

catalog :

MBS8221756

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of HSP70 expression in HepG2 (A), Jurkat (B), Raw264.7 (C), PC12 (D) whole cell lysates.

image 2 :

Immunohistochemical analysis of HSP70 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

product information

catalog number :

MBS8221756

products type :

Antibody

products full name :

Anti-HSP70 Antibody

products short name :

[HSP70]

products name syn :

[HSPA1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-Hom; HSP70-Hom; HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2]

other names :

[heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1-like; heat shock 70kDa protein 1-like; Heat shock 70 kDa protein 1-Hom; HSP70-Hom]

products gene name :

[HSPA1L]

products gene name syn :

[HSPA1A]

other gene names :

[HSPA1L; HSPA1L; HSP70T; hum70t; HSP70-1L; HSP70-HOM; Heat shock 70 kDa protein 1L; HSP70-Hom]

uniprot entry name :

HS71L_HUMAN

clonality :

Polyclonal

host :

unknown

reactivity :

Human, Mouse, Rat, Bovine, Dog, Monkey, Porcine

sequence length :

641

specificity :

Recognizes endogenous levels of HSP70 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB (1/500 - 1/1000), IHC (1/100 - 1/200)

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HSP70. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to HSP70

ncbi gi num :

124256496

ncbi acc num :

NP_005518.3

ncbi gb acc num :

NM_005527.3

uniprot acc num :

P34931

ncbi mol weight :

70,375 Da

ncbi pathways :

Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Attenuation Phase Pathway (1270424); Cellular Response To Heat Stress Pathway (1270421); Cellular Responses To Stress Pathway (1270414); Endocytosis Pathway (102279); Endocytosis Pathway (102181); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Estrogen Signaling Pathway (799177)

ncbi summary :

This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]

uniprot summary :

HSPA1L: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Not induced by heat shock. Expressed in spermatids. Belongs to the heat shock protein 70 family. Protein type: Mitochondrial; Heat shock protein; Chaperone. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: nucleoplasm; signalosome; mitochondrial matrix; cytosol. Molecular Function: protein binding; unfolded protein binding; ATP binding. Biological Process: binding of sperm to zona pellucida; protein refolding; response to unfolded protein

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage