product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-MYO6 Antibody
catalog :
MBS822086
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of MYO6 expression in MCF7 (A) whole cell lysates.
product information
catalog number :
MBS822086
products type :
Antibody
products full name :
Anti-MYO6 Antibody
products short name :
[MYO6]
products name syn :
[KIAA0389; Unconventional myosin-VI; Unconventional myosin-6]
other names :
[unconventional myosin-VI isoform 2; Unconventional myosin-VI; unconventional myosin-VI; unconventional myosin-6; myosin VI; Unconventional myosin-6]
products gene name :
[MYO6]
other gene names :
[MYO6; MYO6; DFNA22; DFNB37; KIAA0389]
uniprot entry name :
MYO6_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Chicken, Pig
specificity :
Recognizes endogenous levels of MYO6 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MYO6. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to MYO6
ncbi gi num :
665505983
ncbi acc num :
NP_001287828.1
ncbi gb acc num :
NM_001300899.1
uniprot acc num :
Q9UM54
ncbi pathways :
Gap Junction Degradation Pathway (105933); Gap Junction Trafficking Pathway (105927); Gap Junction Trafficking And Regulation Pathway (105926); Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway (106536); Membrane Trafficking Pathway (106160); Neuronal System Pathway (106513); Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway (106534); Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway (137918); Trafficking Of AMPA Receptors Pathway (106537); Transmission Across Chemical Synapses Pathway (106516)
ncbi summary :
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
uniprot summary :
MYO6: a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins. Protein type: Motility/polarity/chemotaxis; Actin-binding; Motor. Chromosomal Location of Human Ortholog: 6q13. Cellular Component: Golgi apparatus; nuclear membrane; microvillus; lysosomal membrane; cytoplasmic membrane-bound vesicle; clathrin coated vesicle membrane; coated pit; DNA-directed RNA polymerase II, holoenzyme; cell cortex; clathrin-coated endocytic vesicle; cytosol; nucleoplasm; filamentous actin; ruffle; cell soma; membrane; perinuclear region of cytoplasm; endocytic vesicle; apical part of cell; axon; cytoplasm; unconventional myosin complex; plasma membrane; nucleus. Molecular Function: actin filament binding; calmodulin binding; minus-end directed microfilament motor activity; protein binding; motor activity; actin binding; ADP binding; ATP binding. Biological Process: response to drug; inner ear morphogenesis; DNA damage response, signal transduction by p53 class mediator; metabolic process; actin filament-based movement; regulation of synaptic plasticity; auditory receptor cell differentiation; regulation of secretion; locomotory behavior; endocytosis; synaptic transmission; intracellular protein transport; synaptogenesis; sensory perception of sound; glutamate secretion; dendrite development; positive regulation of transcription from RNA polymerase II promoter; protein targeting. Disease: Deafness, Autosomal Recessive 37; Deafness, Autosomal Dominant 22
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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