Anti-Beta-3 Adrenergic Receptor Antibody | MyBioSource MBS8220053 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-Beta-3 Adrenergic Receptor Antibody

catalog :

MBS8220053

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of Beta-3 Adrenergic Receptor expression in MCF7 (A), mouse kidney (B), rat liver (C) whole cell lysates.

product information

catalog number :

MBS8220053

products type :

Antibody

products full name :

Anti-Beta-3 Adrenergic Receptor Antibody

products short name :

[Beta-3 Adrenergic Receptor]

products name syn :

[ADRB3R; B3AR; Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptor]

other names :

[beta-3 adrenergic receptor; Beta-3 adrenergic receptor; beta-3 adrenergic receptor; adrenoceptor beta 3; Beta-3 adrenoreceptor; Beta-3 adrenoceptor]

products gene name :

[ADRB3]

other gene names :

[ADRB3; ADRB3; BETA3AR; ADRB3R; B3AR; Beta-3 adrenoceptor]

uniprot entry name :

ADRB3_HUMAN

clonality :

Polyclonal

host :

unknown

reactivity :

Human, Mouse, Rat

specificity :

Recognizes endogenous levels of Beta-3 Adrenergic Receptor protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB)

app notes :

WB (1/500 - 1/1000)

image1 heading :

Western Blot (WB)

other info1 :

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Beta-3 Adrenergic Receptor. The exact sequence is proprietary.

other info2 :

Source: Rabbit

products description :

Rabbit polyclonal antibody to Beta-3 Adrenergic Receptor

ncbi gi num :

4557267

ncbi acc num :

NP_000016.1

ncbi gb acc num :

NM_000025.2

uniprot acc num :

P13945

ncbi pathways :

Adrenoceptors Pathway (1269555); Amine Ligand-binding Receptors Pathway (1269553); Calcium Regulation In The Cardiac Cell Pathway (198906); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Endocytosis Pathway (102279); Endocytosis Pathway (102181); G Alpha (s) Signalling Events Pathway (1269575); GPCR Downstream Signaling Pathway (1269574)

ncbi summary :

The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq, Feb 2009]

uniprot summary :

ADRB3: Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1. Chromosomal Location of Human Ortholog: 8p12. Cellular Component: integral to plasma membrane; plasma membrane; nucleus; receptor complex. Molecular Function: beta3-adrenergic receptor activity; protein binding; protein homodimerization activity; beta-3 adrenergic receptor binding; norepinephrine binding; epinephrine binding; beta-adrenergic receptor activity. Biological Process: arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway; receptor-mediated endocytosis; diet induced thermogenesis; generation of precursor metabolites and energy; negative regulation of multicellular organism growth; eating behavior; adenylate cyclase activation; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; response to antibiotic; G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of MAPKKK cascade; heat generation; carbohydrate metabolic process; brown fat cell differentiation; energy reserve metabolic process; response to cold; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure; aging. Disease: Obesity

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage