catalog number :
MBS821939
products full name :
Anti-GPR81 Antibody
products short name :
[GPR81]
products name syn :
[GPR104; GPR81; HCA1; Hydroxycarboxylic acid receptor 1; G-protein coupled receptor 104; G-protein coupled receptor 81]
other names :
[hydroxycarboxylic acid receptor 1; Hydroxycarboxylic acid receptor 1; hydroxycarboxylic acid receptor 1; lactate receptor 1; G protein-coupled receptor 81; G-protein coupled receptor 81; G protein-coupled receptor 104; G-protein coupled receptor 104; hydroxy-carboxylic acid receptor 1; T-cell activation G protein-coupled receptor; hydroxycarboxylic acid receptor 1; G-protein coupled receptor 104; G-protein coupled receptor 81]
products gene name :
[HCAR1]
other gene names :
[HCAR1; HCAR1; HCA1; GPR81; LACR1; FKSG80; GPR104; TAGPCR; TA-GPCR; GPR104; GPR81; HCA1]
uniprot entry name :
HCAR1_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of GPR81 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Gene Symbol: HCAR1
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GPR81. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to GPR81
ncbi acc num :
NP_115943.1
ncbi gb acc num :
NM_032554.3
ncbi mol weight :
39,295 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Hydroxycarboxylic Acid-binding Receptors Pathway (833831); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); CAMP Signaling Pathway (1017634); CAMP Signaling Pathway (1019520)
ncbi summary :
G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Feb 2005]
uniprot summary :
Gpr81: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: plasma membrane; integral to membrane. Molecular Function: G-protein coupled receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; response to estradiol stimulus