product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-CD279 Antibody
catalog :
MBS821930
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS821930 image 1
Western blot analysis of CD279 expression in THP1 (A), HepG2 (B), mouse liver (C), H9C2 (D) whole cell lysates.
product information
catalog number :
MBS821930
products type :
Antibody
products full name :
Anti-CD279 Antibody
products short name :
[CD279]
products name syn :
[PD1; Programmed cell death protein 1; Protein PD-1; hPD-1; CD279]
other names :
[programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2; programmed cell death 1; CD_antigen: CD279]
products gene name :
[PDCD1]
other gene names :
[PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1]
uniprot entry name :
PDCD1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
288
specificity :
Recognizes endogenous levels of CD279 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD279. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to CD279
ncbi gi num :
167857792
ncbi acc num :
NP_005009.2
ncbi gb acc num :
NM_005018.2
uniprot acc num :
Q15116
ncbi mol weight :
31,647 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Costimulation By The CD28 Family Pathway (119552); Immune System Pathway (106386); PD-1 Signaling Pathway (119557); T Cell Receptor Signaling Pathway (83080); T Cell Receptor Signaling Pathway (491)
ncbi summary :
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
uniprot summary :
PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse exhausted T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells. Protein type: Apoptosis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q37.3. Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane. Molecular Function: protein binding; signal transducer activity. Biological Process: apoptosis; multicellular organismal development; T cell costimulation; signal transduction; humoral immune response. Disease: Systemic Lupus Erythematosus
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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