product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Topoisomerase 3 alpha Antibody
catalog :
MBS8213918
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, dog, cow, zebrafish
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of Topoisomerase 3 alpha expression in A549 (A), MCF7 (B) whole cell lysates.
product information
catalog number :
MBS8213918
products type :
Antibody
products full name :
Anti-Topoisomerase 3 alpha Antibody
products short name :
[Topoisomerase 3 alpha]
products name syn :
[TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha]
other names :
[DNA topoisomerase 3-alpha; DNA topoisomerase 3-alpha; DNA topoisomerase 3-alpha; topoisomerase (DNA) III alpha; DNA topoisomerase III alpha]
products gene name :
[TOP3A]
other gene names :
[TOP3A; TOP3A; TOP3; ZGRF7; TOP3]
uniprot entry name :
TOP3A_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Bovine, Dog, Zebrafish
sequence length :
1001
specificity :
Recognizes endogenous levels of Topoisomerase 3 alpha protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Topoisomerase 3 alpha. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to Topoisomerase 3 alpha
ncbi gi num :
10835218
ncbi acc num :
NP_004609.1
ncbi gb acc num :
NM_004618.3
uniprot acc num :
Q13472
ncbi mol weight :
101,208 Da
ncbi pathways :
Bloom's Syndrome Complex Pathway (413477); Bloom's Syndrome Complex Pathway (890629); Cell Cycle Pathway (1269741); Fanconi Anemia Pathway (377262); Fanconi Anemia Pathway (377128); Homologous Recombination Pathway (83046); Homologous Recombination Pathway (454); Meiosis Pathway (1269865); Meiotic Recombination Pathway (1269866)
ncbi summary :
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008]
uniprot summary :
TOP3A: a DNA topoisomerase. Reduces the number of supercoils in a highly negatively supercoiled DNA. Two alternatively spliced human isoforms have been described. Protein type: EC 5.99.1.2; Isomerase. Chromosomal Location of Human Ortholog: 17p11.2. Cellular Component: PML body; chromosome; nucleus. Molecular Function: protein binding; DNA binding; zinc ion binding; DNA topoisomerase type I activity. Biological Process: meiosis; DNA topological change
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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