Anti-PAK7 Antibody | MyBioSource MBS821353 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-PAK7 Antibody

catalog :

MBS821353

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of PAK7 expression in SKNSH (A), K562 (B), COS7 (C) whole cell lysates.

image 2 :

Immunohistochemical analysis of PAK7 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

product information

catalog number :

MBS821353

products type :

Antibody

products full name :

Anti-PAK7 Antibody

products short name :

[PAK7]

products name syn :

[KIAA1264; PAK5; Serine/threonine-protein kinase PAK 7; p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7]

other names :

[serine/threonine-protein kinase PAK 7; Serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK 7; PAK-5; PAK-7; protein kinase PAK5; p21-activated kinase 5; p21-activated kinase 7; p21CDKN1A-activated kinase 7; serine/threonine-protein kinase PAK7; p21 protein (Cdc42/Rac)-activated kinase 7; p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7]

products gene name :

[PAK7]

other gene names :

[PAK7; PAK7; PAK5; KIAA1264; PAK5; PAK-5; PAK-7]

uniprot entry name :

PAK7_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse, Rat, Monkey

sequence length :

719

specificity :

Recognizes endogenous levels of PAK7 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB (1/500 - 1/1000), IH (1/100 - 1/200)

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info2 :

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PAK7. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to PAK7

ncbi gi num :

24308191

ncbi acc num :

NP_065074.1

ncbi gb acc num :

NM_020341.3

uniprot acc num :

Q9P286

ncbi mol weight :

80,745 Da

ncbi pathways :

Activation Of Rac Pathway (119530); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); ErbB Signaling Pathway (83049); ErbB Signaling Pathway (458); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)

ncbi summary :

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

uniprot summary :

PAK5: a protein kinase of the STE20 family. Predominantly expressed in brain. Capable of promoting neurite outgrowth, and thus may play a role in neurite development. Associated with microtubule networks and induces microtubule stabilization. Its subcellular localization is tightly regulated during cell cycle progression. Protein type: Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; STE group; STE20 family; PAKB subfamily. Chromosomal Location of Human Ortholog: 20p12. Cellular Component: mitochondrion; cytoplasm; nucleus. Molecular Function: ATP binding; receptor signaling protein serine/threonine kinase activity. Biological Process: cell proliferation; cell migration; apoptosis; locomotory behavior; cytoskeleton organization and biogenesis; learning; mitotic cell cycle; cell growth; signal transduction; protein amino acid phosphorylation; memory

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage