catalog number :
MBS821286
products full name :
Anti-Aquaporin 5 Antibody
products short name :
[Aquaporin 5]
products name syn :
[Aquaporin-5; AQP-5]
other names :
[aquaporin-5; Aquaporin-5; aquaporin-5; aquaporin 5]
products gene name :
[AQP5]
other gene names :
[AQP5; AQP5; PPKB; AQP-5; AQP-5]
uniprot entry name :
AQP5_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of Aquaporin 5 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB (1/500 - 1/1000), IH (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Aquaporin 5. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to Aquaporin 5
ncbi acc num :
NP_001642.1
ncbi gb acc num :
NM_001651.3
ncbi mol weight :
28,292 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (187187); Passive Transport By Aquaporins Pathway (187188); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway (137918); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
uniprot summary :
AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family. Protein type: Membrane protein, integral; Channel, misc.; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: microvillus; integral to plasma membrane; endoplasmic reticulum; apical plasma membrane; plasma membrane; basal plasma membrane. Molecular Function: protein binding; water channel activity; glycerol channel activity. Biological Process: odontogenesis; glycerol transport; cellular water homeostasis; camera-type eye morphogenesis; water transport; carbon dioxide transport; pancreatic juice secretion; excretion; transmembrane transport; saliva secretion