product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-CD32b (pY292) Antibody
catalog :
MBS821220
quantity :
0.03 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of CD32b (pY292) expression in MCF7 pervanadate-treated (A), mouse liver (B), PC12 pervanadate-treated (C) whole cell lysates.
product information
catalog number :
MBS821220
products type :
Antibody
products full name :
Anti-CD32b (pY292) Antibody
products short name :
[CD32b (pY292)]
products name syn :
[CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32]
other names :
[low affinity immunoglobulin gamma Fc region receptor II-b isoform 2; Low affinity immunoglobulin gamma Fc region receptor II-b; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD_antigen: CD32]
products gene name :
[FCGR2B]
other gene names :
[FCGR2B; FCGR2B; CD32; FCG2; CD32B; FCGR2; IGFR2; CD32; FCG2; IGFR2; IgG Fc receptor II-b; Fc-gamma-RIIb; FcRII-b]
uniprot entry name :
FCG2B_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Monkey
sequence length :
290
specificity :
Recognizes endogenous levels of CD32b (pY292) protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD32b. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to CD32b (pY292)
ncbi gi num :
50511932
ncbi acc num :
NP_001002273.1
ncbi gb acc num :
NM_001002273.2
uniprot acc num :
P31994
ncbi pathways :
Adaptive Immune System Pathway (366160); B Cell Receptor Signaling Pathway (198909); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492); BCR Signaling Pathway (138058); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590); Fc-epsilon Receptor I Signaling In Mast Cells Pathway (138050); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413)
ncbi summary :
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
uniprot summary :
FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed. Protein type: Membrane protein, integral; Oncoprotein; Cell surface. Chromosomal Location of Human Ortholog: 1q23. Cellular Component: integral to membrane; plasma membrane. Molecular Function: protein binding; IgG binding. Biological Process: regulation of immune response; viral reproduction; immune response; signal transduction. Disease: Systemic Lupus Erythematosus; Malaria, Susceptibility To
size1 :
0.03 mL
price1 :
165 USD
size2 :
0.1 mL
price2 :
245
size3 :
0.2 mL
price3 :
350
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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