catalog number :
MBS821113
products full name :
Anti-SGLT2 Antibody
products short name :
[SGLT2]
products name syn :
[SGLT2; Sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2]
other names :
[sodium/glucose cotransporter 2; Sodium/glucose cotransporter 2; sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; solute carrier family 5 member 2; low affinity sodium-glucose cotransporter; solute carrier family 5 (sodium/glucose transporter), member 2; solute carrier family 5 (sodium/glucose cotransporter), member 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2]
products gene name :
[SLC5A2]
other gene names :
[SLC5A2; SLC5A2; SGLT2; SGLT2; Na(+)/glucose cotransporter 2]
uniprot entry name :
SC5A2_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of SGLT2 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Entrez Gene: 6524 (Human); 246787 (Mouse); 64522 (Rat). SwissProt: P31639 (Human); Q923I7 (Mouse); P53792 (Rat)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SGLT2. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to SGLT2
ncbi acc num :
NP_003032.1
ncbi gb acc num :
NM_003041.3
ncbi pathways :
Disease Pathway (530764); Glycogen Storage Diseases Pathway (980468); Hexose Transport Pathway (106198); Inositol Transporters Pathway (119575); Metabolism Pathway (477135); Metabolism Of Carbohydrates Pathway (106196); Myoclonic Epilepsy Of Lafora Pathway (980469); Na+-dependent Glucose Transporters Pathway (119574); SLC-mediated Transmembrane Transport Pathway (119558); Transmembrane Transport Of Small Molecules Pathway (106572)
ncbi summary :
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]
uniprot summary :
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: plasma membrane; integral to membrane. Molecular Function: low-affinity glucose:sodium symporter activity. Biological Process: transport; carbohydrate metabolic process; sodium ion transport; glucose transport; transmembrane transport. Disease: Renal Glucosuria