Anti-GRASP55 Antibody | MyBioSource MBS821004 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-GRASP55 Antibody

catalog :

MBS821004

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of GRASP55 expression in HepG2 (A), Raji (B), LOVO (C) whole cell lysates.

image 2 :

Immunohistochemical analysis of GRASP55 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

product information

catalog number :

MBS821004

products type :

Antibody

products full name :

Anti-GRASP55 Antibody

products short name :

[GRASP55]

products name syn :

[GOLPH6; Golgi reassembly-stacking protein 2; GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59]

other names :

[Golgi reassembly-stacking protein 2 isoform 2; Golgi reassembly-stacking protein 2; Golgi reassembly-stacking protein 2; golgi phosphoprotein 6; golgi reassembly stacking protein 2, 55kDa; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59]

products gene name :

[GORASP2]

other gene names :

[GORASP2; GORASP2; p59; GRS2; GOLPH6; GRASP55; GOLPH6; GRS2; GOLPH6; GRASP55]

uniprot entry name :

GORS2_HUMAN

clonality :

Polyclonal

host :

unknown

reactivity :

Human, Mouse, Rat, Bovine

sequence length :

384

specificity :

Recognizes endogenous levels of GRASP55 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

app notes :

WB (1/500 - 1/1000); IHC (1/100 - 1/200); IP (1/10 - 1/100)

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info2 :

Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GRASP55. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to GRASP55

ncbi gi num :

319803020

ncbi acc num :

NP_001188357.1

ncbi gb acc num :

NM_001201428.1

uniprot acc num :

Q9H8Y8

ncbi mol weight :

48,674 Da

ncbi pathways :

Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Golgi Cisternae Pericentriolar Stack Reorganization Pathway (105814); M Phase Pathway (105812); Mitotic Prophase Pathway (105813)

ncbi summary :

This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

uniprot summary :

GRASP55: a golgi reassembly-stacking protein (GRASP) protein involved in the stacking of Golgi cisternae. May be involved in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as the TGF-alpha receptor. Oligomerization of its N-terminal GRASP domain regulates the formation of Golgi stacks, a process that is regulated by phosphorylation within the C-terminal Ser/Pro-rich domain. Forms a RAB2 effector complex with BLZF1 in the medial Golgi. Interacts with members of the p24 cargo receptors. Interacts with CNIH and the cytoplasmic domain of the TGF-alpha receptor, prior its transit in the trans-Golgi. Two alternatively spliced isoforms have been described. Protein type: Vesicle; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 2q31.1. Cellular Component: Golgi membrane; Golgi apparatus; membrane. Molecular Function: protein binding. Biological Process: organelle organization and biogenesis; mitotic cell cycle

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage