product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-RPC Antibody
catalog :
MBS820971
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of RPC expression in HeLa (A), NIH3T3 (B), rat stomach (C) whole cell lysates.
image 2 :
Immunohistochemical analysis of RPC staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
product information
catalog number :
MBS820971
products type :
Antibody
products full name :
Anti-RPC Antibody
products short name :
[RPC]
products name syn :
[RPC; RPC1; RTC1; RTCD1; RNA 3'-terminal phosphate cyclase; RNA cyclase; RNA-3'-phosphate cyclase; RNA terminal phosphate cyclase domain-containing protein 1; RTC domain-containing protein 1]
other names :
[RNA 3'-terminal phosphate cyclase isoform a; RNA 3'-terminal phosphate cyclase; RNA 3'-terminal phosphate cyclase; RTC domain-containing protein 1; RNA terminal phosphate cyclase domain 1; RNA terminal phosphate cyclase domain-containing protein 1; RNA 3'-terminal phosphate cyclase; RNA terminal phosphate cyclase domain-containing protein 1; RTC domain-containing protein 1]
products gene name :
[RTCA]
other gene names :
[RTCA; RTCA; RPC; RTC1; RTCD1; RPC; RPC1; RTC1; RTCD1; RNA cyclase; RNA-3'-phosphate cyclase; RTC domain-containing protein 1]
uniprot entry name :
RTCA_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
379
specificity :
Recognizes endogenous levels of RPC protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB (1/500 - 1/1000), IH (1/100 - 1/200)
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RPC. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to RPC
ncbi gi num :
195927044
ncbi acc num :
NP_001124313.1
ncbi gb acc num :
NM_001130841.1
uniprot acc num :
O00442
ncbi mol weight :
40,709 Da
ncbi summary :
This gene encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
uniprot summary :
RTCD1: Catalyzes the conversion of 3 -phosphate to a 2 ,3 - cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3 P to produce RNA- N3 PP5 (C) and attack of the adjacent 2 -hydroxyl on the 3 - phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. Belongs to the RNA 3 -terminal cyclase family. Type 1 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Ligase; EC 6.5.1.4; RNA-binding. Chromosomal Location of Human Ortholog: 1p21.2. Cellular Component: nucleoplasm; nucleus. Molecular Function: RNA binding; RNA-3 -phosphate cyclase activity; ATP binding. Biological Process: RNA processing
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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