Anti-GPR105 Antibody | MyBioSource MBS820848 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-GPR105 Antibody

catalog :

MBS820848

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of GPR105 expression in MDAMB435 (A), HEK293 (B) whole cell lysates.

image 2 :

Immunohistochemical analysis of GPR105 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

product information

catalog number :

MBS820848

products type :

Antibody

products full name :

Anti-GPR105 Antibody

products short name :

[GPR105]

products name syn :

[GPR105; KIAA0001; P2Y purinoceptor 14; P2Y14; G-protein coupled receptor 105; UDP-glucose receptor]

other names :

[P2Y purinoceptor 14; P2Y purinoceptor 14; P2Y purinoceptor 14; P2Y14 receptor; UDP-glucose receptor; G protein-coupled receptor 105; G-protein coupled receptor 105; G protein coupled receptor for UDP-glucose; purinergic receptor P2Y, G-protein coupled, 14; G-protein coupled receptor 105; UDP-glucose receptor]

products gene name :

[P2RY14]

other gene names :

[P2RY14; P2RY14; P2Y14; BPR105; GPR105; GPR105; KIAA0001; P2Y14]

uniprot entry name :

P2Y14_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

338

specificity :

Recognizes endogenous levels of GPR105 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

app notes :

WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info2 :

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR105. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to GPR105

ncbi gi num :

125625354

ncbi acc num :

NP_001074924.1

ncbi gb acc num :

NM_001081455.1

uniprot acc num :

Q15391

ncbi mol weight :

38,971 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nucleotide-like (purinergic) Receptors Pathway (106373); P2Y Receptors Pathway (106374); Signal Transduction Pathway (477114)

ncbi summary :

The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

P2RY14: Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 3q24-q25.1. Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane. Molecular Function: UDP-activated nucleotide receptor activity; purinergic nucleotide receptor activity, G-protein coupled. Biological Process: G-protein coupled receptor protein signaling pathway

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage