Anti-Laminin alpha 5 Antibody | MyBioSource MBS820658 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-Laminin alpha 5 Antibody

catalog :

MBS820658

quantity :

0.03 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS820658

products type :

Antibody

products full name :

Anti-Laminin alpha 5 Antibody

products short name :

Laminin alpha 5

products name syn :

KIAA0533; KIAA1907; Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

other names :

laminin subunit alpha-5; Laminin subunit alpha-5; laminin subunit alpha-5; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; laminin, alpha 5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

products gene name :

LAMA5

other gene names :

LAMA5; LAMA5; KIAA0533; KIAA1907

uniprot entry name :

LAMA5_HUMAN

clonality :

Polyclonal

reactivity :

Human, Mouse

sequence length :

3695

specificity :

Recognizes endogenous levels of Laminin alpha 5 protein.

purity :

The antibody was purified by immunogen affinity chromatography.

form :

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

app notes :

WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)

other info1 :

Source: Rabbit. Entrez Gene: 3911 (Human); 16776 (Mouse). SwissProt: O15230 (Human); Q61001 (Mouse)

other info2 :

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Laminin alpha 5. The exact sequence is proprietary.

products description :

Rabbit polyclonal antibody to Laminin alpha 5

ncbi gi num :

21264602

ncbi acc num :

NP_005551.3

ncbi gb acc num :

NM_005560.4

uniprot acc num :

O15230

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Degradation Of The Extracellular Matrix Pathway (576263); ECM Proteoglycans Pathway (833812); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067)

ncbi summary :

This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]

uniprot summary :

LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Extracellular matrix. Chromosomal Location of Human Ortholog: 20q13.2-q13.3. Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus. Molecular Function: integrin binding; structural molecule activity. Biological Process: regulation of cell adhesion; integrin-mediated signaling pathway; focal adhesion formation; endothelial cell differentiation; extracellular matrix organization and biogenesis; cell migration; muscle development; regulation of embryonic development; cytoskeleton organization and biogenesis; cell recognition; regulation of cell migration; odontogenesis of dentine-containing teeth; regulation of cell proliferation; cell proliferation; extracellular matrix disassembly; embryonic development; morphogenesis of embryonic epithelium; hair follicle development; ureteric bud branching; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; lung development

size1 :

0.03 mL

price1 :

155 USD

size2 :

0.1 mL

price2 :

220

size3 :

0.2 mL

price3 :

295

more info or order :

MyBioSource product webpage